From: owner-ammf-digest@smoe.org (alt.music.moxy-fruvous digest) To: ammf-digest@smoe.org Subject: alt.music.moxy-fruvous digest V14 #11751 Reply-To: ammf@fruvous.com Sender: owner-ammf-digest@smoe.org Errors-To: owner-ammf-digest@smoe.org Precedence: bulk alt.music.moxy-fruvous digest Thursday, July 6 2023 Volume 14 : Number 11751 Today's Subjects: ----------------- Tvidler: An ear-friendly earwax removal ["Earwax" Subject: Tvidler: An ear-friendly earwax removal Tvidler: An ear-friendly earwax removal http://littlecaesaresurevy.shop/D4oNHstg6d2g33kZxhB_b3UzliSHIzLOKCxTG5QvwEevV9-Ueg http://littlecaesaresurevy.shop/4oqyeey9FWfcazfevv5qhRl1_ybs142mVnhegDJvZ3p_ZSQBCg Several other diseases that cause inflammation of the lung increase one's risk of lung cancer. This association is strongest for chronic obstructive pulmonary disorder b the risk is highest in those with the most inflammation, and reduced in those whose inflammation is treated with inhaled corticosteroids. Other inflammatory lung and immune system diseases such as alpha-1 antitrypsin deficiency, interstitial fibrosis, scleroderma, Chlamydia pneumoniae infection, tuberculosis, and HIV infection are associated with increased risk of developing lung cancer. Epstein-Barr virus is associated with the development of the rare lung cancer lymphoepithelioma-like carcinoma in people from Asia, but not in people from Western nations. A role for several other infectious agents b namely human papillomaviruses, BK virus, JC virus, human cytomegalovirus, SV40, measles virus, and Torque teno virus b in lung cancer development has been studied but remains inconclusive as of 2020. Genetics Particular gene combinations may make some people more susceptible to lung cancer. Close family members of those with lung cancer have around twice the risk of developing lung cancer as an average person, even after controlling for occupational exposure and smoking habits. Genome-wide association studies have identified many gene variants associated with lung cancer risk, each of which contributes a small risk increase. Many of these genes participate in pathways known to be involved in carcinogenesis, namely DNA repair, inflammation, the cell division cycle, cellular stress responses, and chromatin remodeling. Some rare genetic disorders that increase the risk of various cancers also increase the risk of lung cancer, namely retinoblastoma and Li Fraumeni syndrome. Pathogenesis As with all cancers, lung cancer is triggered by mutations that allow tumor cells to endlessly multiply, stimulate blood vessel growth, avoid apoptosis (programmed cell death), generate pro-growth signalling molecules, ignore anti-growth signalling molecules, and eventually spread into surrounding tissue or metastasize throughout the body. Different tumors can acquire these abilities through different mutations, though generally cancer-contributing mutations activate oncogenes and inactivate tumor suppressors. S ------------------------------ End of alt.music.moxy-fruvous digest V14 #11751 ***********************************************